Biofilm inhibitory potential of Oscillatoria tenuis against Candida albicans

Prokaryotic autotrophs have a key role in maintaining the sustainability of nature. Their secondary metabolites and stored chemicals wide utility human life. Cyanophytes, primitive producers, can become necessity modern world as they enormous unexplored features. Candida albicans, an opportunistic pathogen having multidrug resistance, fallout health concerns animal hosts. This study focused on antibiofilm potential Oscillatoria tenuis NTAPD 02, isolated from hydrocarbon-polluted area against hyphal switching albicans. Ethanolic extract algal sample, OEE, was taken to perform biofilm quantification test CLSM studies determine The MBIC for OEE found be 30 µg/mL C. albicans also shows 70.8% reduction fungal biofilm. GC-MS FTIR analysis illustrates presence potent phenolic hydrocarbons anti-proliferative effect. stress generative elegans (500 µg/mL). ROS generation worms intensified by increased concentration OEE. proves that tenuis, considered alga invasions.